Harvard-trained ophthalmologist, Dr. Mandell founded LayerBio with the aim of developing a drug-eluting IOL for cataract surgery. He is co-inventor of Oyster Point Pharma’s OC-01 treatment for dry eye disease and Aldeyra’s reproxalap eye drop for ocular inflammation. He has personally contributed to more than a dozen Investigational New Drug (IND) applications and overseen the conduct of numerous Phase 1 through Phase 3 clinical trials in the field of ophthalmology. He currently serves as strategic advisor to Aramis Biosciences, a Harvard spin-off developing novel therapies for eye disease and as Medical Monitor for the National Eye Institute at the National Institutes of Health.