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Understanding Material Properties for HME Process Optimization in ASD Formulations
3/11/2019
16:15 - 16:50
Demonstrate connection between ASD thermodynamic properties and HME manufacturing process
Application drug/polymer phase diagram as a tool for HME risk assessment
Demonstrate correlation between drug/polymer phase diagram, drug load, rheology, and HME process.
Correlating drug product CQA (residual crystallinity, chemical/thermal stability) to drug/polymer phase diagram and HME process parameters
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