François-Xavier Legrand, Université Paris-Saclay
François-Xavier Legrand
Associate Professor
Université Paris-Saclay

François-Xavier LEGRAND was born in Béthune (France) in 1984. He completed a Ph.D in Organic and Macromolecular Chemistry at the University of Artois in November 2010 under the direction of Professors Eric Monflier and Sébastien Tilloy. During his Ph.D. in the Catalysis and Solid Chemistry Unit, he worked on the development of novel cyclodextrin-based transporters and ligands for organometallic catalytic processes in aqueous media. He then obtained a Post-Doctoral Engineer-Researcher position in the Laboratory of Structure and Dynamics by NMR at the French Alternative Energies and Atomic Energy Commission in Saclay and worked on the interaction of gases with water-soluble cage molecules by nuclear magnetic resonance and gas hyperpolarization for NMR applications. In September 2011, he was appointed Associate Professor at Paris-Saclay University (formerly Paris-Sud) and joined the team Multiscale Physical Chemistry for Pharmaceutical Sciences (formerly Physico-Chemistry of Multiphasic Systems) at the Institut Galien Paris-Saclay. His current work is focused on the design and the characterization of complex supramolecular systems based on cyclodextrins and / or lipids with or without molecules of interest for drug delivery, especially for the treatment of acute myeloid leukemia. Since 2018, he has been interested in the effect of deep eutectic solvents on the skin for pharmaceutical and cosmetic applications as well as their use for the cutaneous delivery of therapeutic molecules. In this context, he was awarded a young researcher grant from the French National Agency for Research in 2019 to study the use of deep eutectic solvents for the treatment of cutaneous leishmaniasis. More recently, he has also focused on better understanding the behavior of deep eutectic solvents after oral administration.